A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin

Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatological disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death. TEN is a disease of both children and ad...

Full description

Bibliographic Details
Main Authors: Bharti Bhandari, Ragini Singh, Mritunjay Kumar, Aditya Saun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Paediatric Dermatology
Subjects:
Online Access:http://www.ijpd.in/article.asp?issn=2319-7250;year=2019;volume=20;issue=3;spage=258;epage=260;aulast=Bhandari
id doaj-4944a1e7be3d42f3b21ce061c2bebfa0
record_format Article
spelling doaj-4944a1e7be3d42f3b21ce061c2bebfa02020-11-25T01:00:24ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502019-01-0120325826010.4103/ijpd.IJPD_76_17A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulinBharti BhandariRagini SinghMritunjay KumarAditya SaunToxic epidermal necrolysis (TEN) is a potentially life-threatening dermatological disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death. TEN is a disease of both children and adults, but TEN in early infancy is a rare event; in literature, only few cases in infants aged <6 months have been reported so far. We reported a case of a 6-week-old infant who developed TEN after some local off-label medication for abdominal colic. After intravenous immunoglobulin treatment, the infant showed dramatic improvement without any complications.http://www.ijpd.in/article.asp?issn=2319-7250;year=2019;volume=20;issue=3;spage=258;epage=260;aulast=BhandariInfancyintravenous immunoglobulintoxic epidermal necrolysis
collection DOAJ
language English
format Article
sources DOAJ
author Bharti Bhandari
Ragini Singh
Mritunjay Kumar
Aditya Saun
spellingShingle Bharti Bhandari
Ragini Singh
Mritunjay Kumar
Aditya Saun
A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
Indian Journal of Paediatric Dermatology
Infancy
intravenous immunoglobulin
toxic epidermal necrolysis
author_facet Bharti Bhandari
Ragini Singh
Mritunjay Kumar
Aditya Saun
author_sort Bharti Bhandari
title A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
title_short A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
title_full A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
title_fullStr A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
title_full_unstemmed A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin
title_sort rare case of toxic epidermolysis necrolysis in early infancy: successfully treated with intravenous immunoglobulin
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Paediatric Dermatology
issn 2319-7250
publishDate 2019-01-01
description Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatological disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death. TEN is a disease of both children and adults, but TEN in early infancy is a rare event; in literature, only few cases in infants aged <6 months have been reported so far. We reported a case of a 6-week-old infant who developed TEN after some local off-label medication for abdominal colic. After intravenous immunoglobulin treatment, the infant showed dramatic improvement without any complications.
topic Infancy
intravenous immunoglobulin
toxic epidermal necrolysis
url http://www.ijpd.in/article.asp?issn=2319-7250;year=2019;volume=20;issue=3;spage=258;epage=260;aulast=Bhandari
work_keys_str_mv AT bhartibhandari ararecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT raginisingh ararecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT mritunjaykumar ararecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT adityasaun ararecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT bhartibhandari rarecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT raginisingh rarecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT mritunjaykumar rarecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
AT adityasaun rarecaseoftoxicepidermolysisnecrolysisinearlyinfancysuccessfullytreatedwithintravenousimmunoglobulin
_version_ 1725213652852670464