Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report
Abstract Background Bilateral thalamic lesions are rare. Here, we describe a case of probable acute disseminating encephalomyelitis (ADEM) with symmetrical bilateral thalamic lesions. Case presentation An 85-year-old man presented with weakness of the lower limbs and urinary retention for 1 day, soo...
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doaj-494c9c1142d74113a8a5ab1ef056f3f52020-11-25T03:07:30ZengBMCBMC Neurology1471-23772020-07-012011410.1186/s12883-020-01834-wBilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case reportYiming Zheng0Wei Zhang1Hongjun Hao2Feng Gao3Department of Neurology, Peking University First HospitalDepartment of Neurology, Peking University First HospitalDepartment of Neurology, Peking University First HospitalDepartment of Neurology, Peking University First HospitalAbstract Background Bilateral thalamic lesions are rare. Here, we describe a case of probable acute disseminating encephalomyelitis (ADEM) with symmetrical bilateral thalamic lesions. Case presentation An 85-year-old man presented with weakness of the lower limbs and urinary retention for 1 day, soon followed by coma. He had an H1N1 influenza vaccination 3 months ago. A lumbar puncture showed positive oligoclonal bands and negative results for anti-AQP4 antibodies. A head MRI demonstrated focal symmetrical bilateral thalamic lesions. An MRI of the thoracic spinal cord showed longitudinally extensive lesions in the spinal cord. He was diagnosed with probable ADEM. Despite being treated with IVIG, the patient remained unconscious and died a month later from pneumonia. Conclusions In cases with bilateral thalamic lesions, the possibility of ADEM should be considered. The characteristics of the thalamic lesions and imaging findings in other parts of the brain or spinal cord should be taken into account in association with the clinical and laboratory information in making a correct diagnosis.http://link.springer.com/article/10.1186/s12883-020-01834-wADEMNeurology imageThalamic lesions |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yiming Zheng Wei Zhang Hongjun Hao Feng Gao |
spellingShingle |
Yiming Zheng Wei Zhang Hongjun Hao Feng Gao Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report BMC Neurology ADEM Neurology image Thalamic lesions |
author_facet |
Yiming Zheng Wei Zhang Hongjun Hao Feng Gao |
author_sort |
Yiming Zheng |
title |
Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
title_short |
Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
title_full |
Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
title_fullStr |
Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
title_full_unstemmed |
Bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
title_sort |
bilateral thalamic lesions in a patient with probable acute disseminating encephalomyelitis: a case report |
publisher |
BMC |
series |
BMC Neurology |
issn |
1471-2377 |
publishDate |
2020-07-01 |
description |
Abstract Background Bilateral thalamic lesions are rare. Here, we describe a case of probable acute disseminating encephalomyelitis (ADEM) with symmetrical bilateral thalamic lesions. Case presentation An 85-year-old man presented with weakness of the lower limbs and urinary retention for 1 day, soon followed by coma. He had an H1N1 influenza vaccination 3 months ago. A lumbar puncture showed positive oligoclonal bands and negative results for anti-AQP4 antibodies. A head MRI demonstrated focal symmetrical bilateral thalamic lesions. An MRI of the thoracic spinal cord showed longitudinally extensive lesions in the spinal cord. He was diagnosed with probable ADEM. Despite being treated with IVIG, the patient remained unconscious and died a month later from pneumonia. Conclusions In cases with bilateral thalamic lesions, the possibility of ADEM should be considered. The characteristics of the thalamic lesions and imaging findings in other parts of the brain or spinal cord should be taken into account in association with the clinical and laboratory information in making a correct diagnosis. |
topic |
ADEM Neurology image Thalamic lesions |
url |
http://link.springer.com/article/10.1186/s12883-020-01834-w |
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