Pathophysiology of Motor Dysfunction in Parkinson’s Disease as the Rationale for Drug Treatment and Rehabilitation
Cardinal motor features of Parkinson’s disease (PD) include bradykinesia, rest tremor, and rigidity, which appear in the early stages of the disease and largely depend on dopaminergic nigrostriatal denervation. Intermediate and advanced PD stages are characterized by motor fluctuations and dyskinesi...
Main Authors: | Francesca Magrinelli, Alessandro Picelli, Pierluigi Tocco, Angela Federico, Laura Roncari, Nicola Smania, Giampietro Zanette, Stefano Tamburin |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
|
Series: | Parkinson's Disease |
Online Access: | http://dx.doi.org/10.1155/2016/9832839 |
Similar Items
-
Association between Severe Upper Limb Spasticity and Brain Lesion Location in Stroke Patients
by: Alessandro Picelli, et al.
Published: (2014-01-01) -
Electrical Stimulation of Injected Muscles to Boost Botulinum Toxin Effect on Spasticity: Rationale, Systematic Review and State of the Art
by: Alessandro Picelli, et al.
Published: (2021-04-01) -
Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests
by: Angela Federico, et al.
Published: (2015-01-01) -
The Italian Consensus Conference on Pain in Neurorehabilitation: rationale and methodology
by: Tamburin S, et al.
Published: (2016-05-01) -
Relationship between Cognitive Performance and Motor Dysfunction in Patients with Parkinson’s Disease: A Pilot Cross-Sectional Study
by: Valentina Varalta, et al.
Published: (2015-01-01)