Glucocorticoid guides mobilization of bone marrow stem/progenitor cells via FPR and CXCR4 coupling

Glucocorticoid guides mobilization of bone marrow stem/progenitor cells via FPR and CXCR4 coupling

Abstract Background Our previous studies have proved the efficient exogenous repairing responses via bone marrow stem and progenitor cells (BMSPCs). However, the trafficking of endogenous bone marrow stem and progenitor cells to and from the bone marrow (BM) is a highly regulated process that remain...

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Bibliographic Details
Main Authors: Wenting Gao, Xuetao Yang, Juan Du, Haiyan Wang, Hejiang Zhong, Jianxin Jiang, Ce Yang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow
Corticotropin-releasing hormone
Glucocorticoids
Hypothalamic-pituitary-adrenal (HPA) axis
Formyl peptide receptor
Stem/progenitor cells
Online Access:https://doi.org/10.1186/s13287-020-02071-1

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