In vitro free radical scavenging activity of Ixora coccinea L
Antioxidant activity of the methanol extract of Ixora coccinea L. was determined by DPPH free radical scavenging assay, reducing power and total antioxidant capacity using phosphomolybdenum method. Preliminary phytochemical screening revealed that the extract of the flowerof I. coccinea possesses f...
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doaj-498161cf87de4125a34f90f887c32c9e2020-11-24T21:20:51ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882008-07-013210.3329/bjp.v3i2.838In vitro free radical scavenging activity of Ixora coccinea LMoni Rani Saha0Md. Ashraful Alam1Raushanara Akter2Rumana Jahangir3Phytochemistry and Pharmacology Laboratory, Department of Pharmacy, Stamford University Bangladesh, Dhaka 1217Phytochemistry and Pharmacology Laboratory, Department of Pharmacy, Stamford University Bangladesh, Dhaka 1217Phytochemistry and Pharmacology Laboratory, Department of Pharmacy, Stamford University Bangladesh, Dhaka 1217Phytochemistry and Pharmacology Laboratory, Department of Pharmacy, Stamford University Bangladesh, Dhaka 1217 Antioxidant activity of the methanol extract of Ixora coccinea L. was determined by DPPH free radical scavenging assay, reducing power and total antioxidant capacity using phosphomolybdenum method. Preliminary phytochemical screening revealed that the extract of the flowerof I. coccinea possesses flavonoids, steroids and tannin materials. The extract showed significant activities in all antioxidant assays compared to the standard antioxidant in a dose dependent manner and remarkable activities to scavenge reactive oxygen species (ROS) may be attributed to the high amount of hydrophilic phenolics. In DPPH radical scavenging assay the IC50 value of the extract was found to be 100.53 μg/mL while ascorbic acid had the IC50value 58.92 μg/mL. Moreover, I. coccinea extract showed strong reducing power and total antioxidant capacity. https://www.banglajol.info/index.php/BJP/article/view/838AntioxidantFree radicalIxora coccinea |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Moni Rani Saha Md. Ashraful Alam Raushanara Akter Rumana Jahangir |
spellingShingle |
Moni Rani Saha Md. Ashraful Alam Raushanara Akter Rumana Jahangir In vitro free radical scavenging activity of Ixora coccinea L Bangladesh Journal of Pharmacology Antioxidant Free radical Ixora coccinea |
author_facet |
Moni Rani Saha Md. Ashraful Alam Raushanara Akter Rumana Jahangir |
author_sort |
Moni Rani Saha |
title |
In vitro free radical scavenging activity of Ixora coccinea L |
title_short |
In vitro free radical scavenging activity of Ixora coccinea L |
title_full |
In vitro free radical scavenging activity of Ixora coccinea L |
title_fullStr |
In vitro free radical scavenging activity of Ixora coccinea L |
title_full_unstemmed |
In vitro free radical scavenging activity of Ixora coccinea L |
title_sort |
in vitro free radical scavenging activity of ixora coccinea l |
publisher |
Bangladesh Pharmacological Society |
series |
Bangladesh Journal of Pharmacology |
issn |
1991-0088 |
publishDate |
2008-07-01 |
description |
Antioxidant activity of the methanol extract of Ixora coccinea L. was determined by DPPH free radical scavenging assay, reducing power and total antioxidant capacity using phosphomolybdenum method. Preliminary phytochemical screening revealed that the extract of the flowerof I. coccinea possesses flavonoids, steroids and tannin materials. The extract showed significant activities in all antioxidant assays compared to the standard antioxidant in a dose dependent manner and remarkable activities to scavenge reactive oxygen species (ROS) may be attributed to the high amount of hydrophilic phenolics. In DPPH radical scavenging assay the IC50 value of the extract was found to be 100.53 μg/mL while ascorbic acid had the IC50value 58.92 μg/mL. Moreover, I. coccinea extract showed strong reducing power and total antioxidant capacity.
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topic |
Antioxidant Free radical Ixora coccinea |
url |
https://www.banglajol.info/index.php/BJP/article/view/838 |
work_keys_str_mv |
AT moniranisaha invitrofreeradicalscavengingactivityofixoracoccineal AT mdashrafulalam invitrofreeradicalscavengingactivityofixoracoccineal AT raushanaraakter invitrofreeradicalscavengingactivityofixoracoccineal AT rumanajahangir invitrofreeradicalscavengingactivityofixoracoccineal |
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