Discovery of long-range inhibitory signaling to ensure single axon formation

Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.

Bibliographic Details
Main Authors: Tetsuya Takano, Mengya Wu, Shinichi Nakamuta, Honda Naoki, Naruki Ishizawa, Takashi Namba, Takashi Watanabe, Chundi Xu, Tomonari Hamaguchi, Yoshimitsu Yura, Mutsuki Amano, Klaus M. Hahn, Kozo Kaibuchi
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00044-2
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spelling doaj-499fc341abbe4dc59222498325b5f8352021-01-31T12:48:46ZengNature Publishing GroupNature Communications2041-17232017-06-018111810.1038/s41467-017-00044-2Discovery of long-range inhibitory signaling to ensure single axon formationTetsuya Takano0Mengya Wu1Shinichi Nakamuta2Honda Naoki3Naruki Ishizawa4Takashi Namba5Takashi Watanabe6Chundi Xu7Tomonari Hamaguchi8Yoshimitsu Yura9Mutsuki Amano10Klaus M. Hahn11Kozo Kaibuchi12Department of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineImaging Platform for Spatio-Temporal Information, Graduate School of Medicine, Kyoto UniversityDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Pharmacology, University of North CarolinaDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineDepartment of Pharmacology, University of North CarolinaDepartment of Cell Pharmacology, Nagoya University Graduate School of MedicineEmerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.https://doi.org/10.1038/s41467-017-00044-2
collection DOAJ
language English
format Article
sources DOAJ
author Tetsuya Takano
Mengya Wu
Shinichi Nakamuta
Honda Naoki
Naruki Ishizawa
Takashi Namba
Takashi Watanabe
Chundi Xu
Tomonari Hamaguchi
Yoshimitsu Yura
Mutsuki Amano
Klaus M. Hahn
Kozo Kaibuchi
spellingShingle Tetsuya Takano
Mengya Wu
Shinichi Nakamuta
Honda Naoki
Naruki Ishizawa
Takashi Namba
Takashi Watanabe
Chundi Xu
Tomonari Hamaguchi
Yoshimitsu Yura
Mutsuki Amano
Klaus M. Hahn
Kozo Kaibuchi
Discovery of long-range inhibitory signaling to ensure single axon formation
Nature Communications
author_facet Tetsuya Takano
Mengya Wu
Shinichi Nakamuta
Honda Naoki
Naruki Ishizawa
Takashi Namba
Takashi Watanabe
Chundi Xu
Tomonari Hamaguchi
Yoshimitsu Yura
Mutsuki Amano
Klaus M. Hahn
Kozo Kaibuchi
author_sort Tetsuya Takano
title Discovery of long-range inhibitory signaling to ensure single axon formation
title_short Discovery of long-range inhibitory signaling to ensure single axon formation
title_full Discovery of long-range inhibitory signaling to ensure single axon formation
title_fullStr Discovery of long-range inhibitory signaling to ensure single axon formation
title_full_unstemmed Discovery of long-range inhibitory signaling to ensure single axon formation
title_sort discovery of long-range inhibitory signaling to ensure single axon formation
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-06-01
description Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.
url https://doi.org/10.1038/s41467-017-00044-2
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