Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media.

Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media.

Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic strain variation, serotype, and host response to disease phenotype is incomplete. Using the chinchilla model of otitis media [OM] we investiga...

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Bibliographic Details
Main Authors: Michael L Forbes, Edward Horsey, N Luisa Hiller, Farrel J Buchinsky, Jay D Hayes, James M Compliment, Todd Hillman, Suzanne Ezzo, Kai Shen, Randy Keefe, Karen Barbadora, J Christopher Post, Fen Ze Hu, Garth D Ehrlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2279396?pdf=render

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