BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES.
Osteonecrosis of the jaw is a consequent condition of a variety of local and systemic factors that compromises the bone blood flow. Bisphosphonates are a class of compounds widely used for the treatment of disorders of bone metabolism, such as bone metastasis and osteoporosis. Bisphosphonates-in...
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Universidade Estadual do Sudoeste da Bahia
2012-08-01
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doaj-4a07f113ffec4868ac675905d5b3356f2020-11-24T22:42:52ZporUniversidade Estadual do Sudoeste da BahiaRevista Saúde.com1809-07611809-07612012-08-01826978BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES.Candice Belchior Duplat0Denis Damião Costa1Antônio Fernando Pereira Falcão2Universidade Federal da Bahia. Salvador – Bahia - BrasilUniversidade Federal da Bahia. Salvador – Bahia - BrasilUniversidade Federal da Bahia. Salvador – Bahia - BrasilOsteonecrosis of the jaw is a consequent condition of a variety of local and systemic factors that compromises the bone blood flow. Bisphosphonates are a class of compounds widely used for the treatment of disorders of bone metabolism, such as bone metastasis and osteoporosis. Bisphosphonates-induced osteonecrosis of the jaw is a new complication, published for the first time at 2003, and can be defined as an unexpected necrosis development on the oral cavity in patients who received bisphosphonates and were not being treated with head and neck radiotherapy. Radiographies show radiolucent zones or sclerotic bone and, in some cases, show areas with delayed or absent bone remodeling after extraction, remain the socket cavity. The treatment can be done in accordance with the condition stage, since management of 0,12% chlorhexidine and antibiotics until laser utilization, hyperbaric oxygen, surgical debridement and resection. It is important to promote more communication between physicians and dentists to guarantee dental attention during the bisphosphonate administration, establishing oral health and preventing complications, such as osteonecrosis induced by this medication. http://www.uesb.br/revista/rsc/ojs/index.php/rsc/article/view/173/204Bone DiseasesOsteonecrosisBisphosphonate Associated Osteonecrosis of the Jaw |
collection |
DOAJ |
language |
Portuguese |
format |
Article |
sources |
DOAJ |
author |
Candice Belchior Duplat Denis Damião Costa Antônio Fernando Pereira Falcão |
spellingShingle |
Candice Belchior Duplat Denis Damião Costa Antônio Fernando Pereira Falcão BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. Revista Saúde.com Bone Diseases Osteonecrosis Bisphosphonate Associated Osteonecrosis of the Jaw |
author_facet |
Candice Belchior Duplat Denis Damião Costa Antônio Fernando Pereira Falcão |
author_sort |
Candice Belchior Duplat |
title |
BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. |
title_short |
BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. |
title_full |
BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. |
title_fullStr |
BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. |
title_full_unstemmed |
BISPHOSPHONATES-INDUCED OSTEONECROSIS OF THE JAW: PHARMACOLOGY AND CLINICAL PROCEDURES. |
title_sort |
bisphosphonates-induced osteonecrosis of the jaw: pharmacology and clinical procedures. |
publisher |
Universidade Estadual do Sudoeste da Bahia |
series |
Revista Saúde.com |
issn |
1809-0761 1809-0761 |
publishDate |
2012-08-01 |
description |
Osteonecrosis of the jaw is a consequent condition of a variety of
local and systemic factors that compromises the bone blood flow.
Bisphosphonates are a class of compounds widely used for the
treatment of disorders of bone metabolism, such as bone
metastasis and osteoporosis. Bisphosphonates-induced
osteonecrosis of the jaw is a new complication, published for the
first time at 2003, and can be defined as an unexpected necrosis
development on the oral cavity in patients who received
bisphosphonates and were not being treated with head and neck
radiotherapy. Radiographies show radiolucent zones or sclerotic
bone and, in some cases, show areas with delayed or absent bone remodeling after extraction, remain the socket cavity. The treatment can be done in accordance with the condition stage, since management of 0,12% chlorhexidine and antibiotics until laser utilization, hyperbaric oxygen, surgical debridement and resection. It is important to promote more communication between physicians and dentists to guarantee dental attention during the
bisphosphonate administration, establishing oral health and
preventing complications, such as osteonecrosis induced by this
medication.
|
topic |
Bone Diseases Osteonecrosis Bisphosphonate Associated Osteonecrosis of the Jaw |
url |
http://www.uesb.br/revista/rsc/ojs/index.php/rsc/article/view/173/204 |
work_keys_str_mv |
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1725698070031630336 |