Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus

Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus

Abstract Background Chlorhexidine digluconate (CHG) is used as a disinfectant. The emergence of pathogens resistant to the biocide raises health concern. Information on specific efflux mechanisms utilised by bacteria to confer reduced susceptibility to the biocide, may be used to develop ways of pre...

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Bibliographic Details
Main Authors: Molly Mombeshora, Stanley Mukanganyama
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Research Notes
Subjects:
Chlorhexidine digluconate
ABC transporter
Nosocomial pathogens
Efflux pump inhibitor
Online Access:http://link.springer.com/article/10.1186/s13104-017-2637-2

Internet

http://link.springer.com/article/10.1186/s13104-017-2637-2

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