Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
Abstract Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we...
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BMC
2021-03-01
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| Series: | Microbiome |
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| Online Access: | https://doi.org/10.1186/s40168-021-01024-x |
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doaj-4a414026b394479da62a3a99b196722f2021-03-21T12:48:44ZengBMCMicrobiome2049-26182021-03-019111810.1186/s40168-021-01024-xIntestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunitiesXiaoyan Wu0Yaoyao Xia1Fang He2Congrui Zhu3Wenkai Ren4State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural UniversityState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural UniversityCollege of Animal Science and Technology, Southwest UniversityCollege of Veterinary Medicine, Kansas State UniversityState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural UniversityAbstract Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. Video Abstract.https://doi.org/10.1186/s40168-021-01024-xIntestinal mycobiotaIntestinal immunityGut-liver axisGut-lung axisGut-brain axis |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Xiaoyan Wu Yaoyao Xia Fang He Congrui Zhu Wenkai Ren |
| spellingShingle |
Xiaoyan Wu Yaoyao Xia Fang He Congrui Zhu Wenkai Ren Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities Microbiome Intestinal mycobiota Intestinal immunity Gut-liver axis Gut-lung axis Gut-brain axis |
| author_facet |
Xiaoyan Wu Yaoyao Xia Fang He Congrui Zhu Wenkai Ren |
| author_sort |
Xiaoyan Wu |
| title |
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| title_short |
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| title_full |
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| title_fullStr |
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| title_full_unstemmed |
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| title_sort |
intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities |
| publisher |
BMC |
| series |
Microbiome |
| issn |
2049-2618 |
| publishDate |
2021-03-01 |
| description |
Abstract Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. Video Abstract. |
| topic |
Intestinal mycobiota Intestinal immunity Gut-liver axis Gut-lung axis Gut-brain axis |
| url |
https://doi.org/10.1186/s40168-021-01024-x |
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