Mannose-decorated hybrid nanoparticles for enhanced macrophage targeting

Our goal was to design nanocarriers that specifically target and deliver therapeutics to polarized macrophages. Mannose receptors are highly overexpressed on polarized macrophages. In this study, we constructed Pluronic® -F127 polymer and tannic acid (TA) based nanoparticles (F127-TA core nanopartic...

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Bibliographic Details
Main Authors: Elham Hatami, Ying Mu, Deanna N. Shields, Subhash C. Chauhan, Santosh Kumar, Theodore J. Cory, Murali M. Yallapu
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081830325X