Point-of-Care System for HTLV-1 Proviral Load Quantification by Digital Mediator Displacement LAMP

Point-of-Care System for HTLV-1 Proviral Load Quantification by Digital Mediator Displacement LAMP

This paper presents a universal point-of-care system for fully automated quantification of human T-cell lymphotropic virus type 1 (HTLV-1) proviral load, including genomic RNA, based on digital reverse RNA transcription and c-DNA amplification by MD LAMP (mediator displacement loop-mediated isotherm...

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Bibliographic Details
Main Authors: Lisa Becherer, Jacob Friedrich Hess, Sieghard Frischmann, Mohammed Bakheit, Hans Nitschko, Silvina Stinco, Friedrich Zitz, Hannes Hofer, Giampiero Porro, Florian Hausladen, Karl Stock, Dominik Drossart, Holger Wurm, Hanna Kuhn, Dominik Huber, Tobias Hutzenlaub, Nils Paust, Mark Keller, Oliver Strohmeier, Simon Wadle, Nadine Borst, Roland Zengerle, Felix von Stetten
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Micromachines
Subjects:
human T-cell lymphotropic virus 1
digital loop-mediated isothermal amplification
point-of-care testing
centrifugal microfluidics
proviral load measurements
Online Access:https://www.mdpi.com/2072-666X/12/2/159

Internet

https://www.mdpi.com/2072-666X/12/2/159

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