Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women
This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire...
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2020-06-01
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doaj-4a64d20cff354e738477493b3fd60f652020-11-25T03:49:20ZengMDPI AGNutrients2072-66432020-06-01121895189510.3390/nu12061895Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal WomenMaría del Pilar del Pozo0Virginia Lope1Inmaculada Criado-Navarro2Roberto Pastor-Barriuso3Nerea Fernández de Larrea4Emma Ruiz5Adela Castelló6Pilar Lucas7Ángeles Sierra8Isabelle Romieu9Véronique Chajès10Feliciano Priego-Capote11Beatriz Pérez-Gómez12Marina Pollán13Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid (UAM), 28049 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Analytical Chemistry, Annex Marie Curie Building, Campus of Rabanales, University of Córdoba, 14014 Córdoba, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainCenter for Research on Population Health, National Institute of Public Health, Cuernavaca 62100, MexicoSection of Nutrition and Metabolism, International Agency for Research on Cancer, 69008 Lyon, FranceDepartment of Analytical Chemistry, Annex Marie Curie Building, Campus of Rabanales, University of Córdoba, 14014 Córdoba, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainDepartment of Epidemiology of Chronic Diseases, National Center for Epidemiology, Carlos III Institute of Health, 28029 Madrid, SpainThis study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography–mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids.https://www.mdpi.com/2072-6643/12/6/1895fatty acidsdesaturation indexobesitybody mass indexfat |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
María del Pilar del Pozo Virginia Lope Inmaculada Criado-Navarro Roberto Pastor-Barriuso Nerea Fernández de Larrea Emma Ruiz Adela Castelló Pilar Lucas Ángeles Sierra Isabelle Romieu Véronique Chajès Feliciano Priego-Capote Beatriz Pérez-Gómez Marina Pollán |
spellingShingle |
María del Pilar del Pozo Virginia Lope Inmaculada Criado-Navarro Roberto Pastor-Barriuso Nerea Fernández de Larrea Emma Ruiz Adela Castelló Pilar Lucas Ángeles Sierra Isabelle Romieu Véronique Chajès Feliciano Priego-Capote Beatriz Pérez-Gómez Marina Pollán Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women Nutrients fatty acids desaturation index obesity body mass index fat |
author_facet |
María del Pilar del Pozo Virginia Lope Inmaculada Criado-Navarro Roberto Pastor-Barriuso Nerea Fernández de Larrea Emma Ruiz Adela Castelló Pilar Lucas Ángeles Sierra Isabelle Romieu Véronique Chajès Feliciano Priego-Capote Beatriz Pérez-Gómez Marina Pollán |
author_sort |
María del Pilar del Pozo |
title |
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women |
title_short |
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women |
title_full |
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women |
title_fullStr |
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women |
title_full_unstemmed |
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women |
title_sort |
serum phospholipid fatty acids levels, anthropometric variables and adiposity in spanish premenopausal women |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-06-01 |
description |
This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography–mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids. |
topic |
fatty acids desaturation index obesity body mass index fat |
url |
https://www.mdpi.com/2072-6643/12/6/1895 |
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