Hidden hearing loss selectively impairs neural adaptation to loud sound environments

Hidden hearing loss selectively impairs neural adaptation to loud sound environments

Hidden hearing loss (HHL) arises through subtle damage to the synapses of hair cells in the inner ear before audiograms reveal hearing threshold shifts. Here, the authors report that HHL in a mouse model disrupts the neural encoding of loud sound environments in the central auditory system.

Bibliographic Details
Main Authors: Warren Michael Henry Bakay, Lucy Anne Anderson, Jose Alberto Garcia-Lazaro, David McAlpine, Roland Schaette
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06777-y
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spelling doaj-4a7605b8f17245938973a6abe767fdcd2021-05-11T10:27:29ZengNature Publishing GroupNature Communications2041-17232018-10-019111110.1038/s41467-018-06777-yHidden hearing loss selectively impairs neural adaptation to loud sound environmentsWarren Michael Henry Bakay0Lucy Anne Anderson1Jose Alberto Garcia-Lazaro2David McAlpine3Roland Schaette4UCL Ear InstituteUCL Ear InstituteUCL Ear InstituteUCL Ear InstituteUCL Ear InstituteHidden hearing loss (HHL) arises through subtle damage to the synapses of hair cells in the inner ear before audiograms reveal hearing threshold shifts. Here, the authors report that HHL in a mouse model disrupts the neural encoding of loud sound environments in the central auditory system.https://doi.org/10.1038/s41467-018-06777-y
collection DOAJ
language English
format Article
sources DOAJ
author Warren Michael Henry Bakay
Lucy Anne Anderson
Jose Alberto Garcia-Lazaro
David McAlpine
Roland Schaette
spellingShingle Warren Michael Henry Bakay
Lucy Anne Anderson
Jose Alberto Garcia-Lazaro
David McAlpine
Roland Schaette
Hidden hearing loss selectively impairs neural adaptation to loud sound environments
Nature Communications
author_facet Warren Michael Henry Bakay
Lucy Anne Anderson
Jose Alberto Garcia-Lazaro
David McAlpine
Roland Schaette
author_sort Warren Michael Henry Bakay
title Hidden hearing loss selectively impairs neural adaptation to loud sound environments
title_short Hidden hearing loss selectively impairs neural adaptation to loud sound environments
title_full Hidden hearing loss selectively impairs neural adaptation to loud sound environments
title_fullStr Hidden hearing loss selectively impairs neural adaptation to loud sound environments
title_full_unstemmed Hidden hearing loss selectively impairs neural adaptation to loud sound environments
title_sort hidden hearing loss selectively impairs neural adaptation to loud sound environments
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-10-01
description Hidden hearing loss (HHL) arises through subtle damage to the synapses of hair cells in the inner ear before audiograms reveal hearing threshold shifts. Here, the authors report that HHL in a mouse model disrupts the neural encoding of loud sound environments in the central auditory system.
url https://doi.org/10.1038/s41467-018-06777-y
work_keys_str_mv AT warrenmichaelhenrybakay hiddenhearinglossselectivelyimpairsneuraladaptationtoloudsoundenvironments
AT lucyanneanderson hiddenhearinglossselectivelyimpairsneuraladaptationtoloudsoundenvironments
AT josealbertogarcialazaro hiddenhearinglossselectivelyimpairsneuraladaptationtoloudsoundenvironments
AT davidmcalpine hiddenhearinglossselectivelyimpairsneuraladaptationtoloudsoundenvironments
AT rolandschaette hiddenhearinglossselectivelyimpairsneuraladaptationtoloudsoundenvironments
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