Age-related changes of the multidrug resistance P-glycoprotein function in normal human peripheral blood T lymphocytes

Age-related changes of the multidrug resistance P-glycoprotein function in normal human peripheral blood T lymphocytes

The multidrug resistance P-glycoprotein is a transmembrane efflux pump expressed by lymphocytes and is involved in their cytolytic activity. In the present study, we investigated the age-related changes of P-glycoprotein function in normal peripheral blood lymphocytes. Blood samples from 90 normal v...

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Bibliographic Details
Main Authors:	C.G. Machado, R.T. Calado, A.B. Garcia, R.P. Falcão
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2003-12-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	P-glycoprotein Multidrug resistance Lymphocytes Rhodamine 123 Flow cytometry
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001200006

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