Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia.
BACKGROUND: Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but there is a considerable fraction of patients experiencing a poor outcome. There is a need for better prognostic markers and aberrant DNA methylation is a candidate in other malignancies, but its potentia...
Main Authors: | Magnus Borssén, Lars Palmqvist, Kristina Karrman, Jonas Abrahamsson, Mikael Behrendtz, Jesper Heldrup, Erik Forestier, Göran Roos, Sofie Degerman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3675104?pdf=render |
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