Hepatoprotective and antioxidant effect of Carissa spinarum root extract against CCl4 and paracetamol-induced hepatic damage in rats

Hepatoprotective and antioxidant effect of Carissa spinarum root extract against CCl4 and paracetamol-induced hepatic damage in rats

Ethanolic extract of the roots of C. spinarum was evaluated for hepato-protective and antioxidant activities in rats. Oral pre-treatment with ethanolic extract (100, 200 and 400 mg/kg) showed significant hepatoprotective activity against CCl4 and paracetamol-induced hepatotoxicity by decreasing the...

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Bibliographic Details
Main Author: Karunakar Hegde, Arun B. Joshi
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2010-06-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Carissa spinarum
Hepatoprotection
Oxidative stress
Online Access:http://www.banglajol.info/index.php/BJP/article/view/5681/4853

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