Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis

A 54-year-old woman with a mechanical mitral valve replacement presented with recurrent admissions for pneumonia and pulmonary edema. Multimodality imaging revealed mobile masses on the prosthesis and discrepant point of care and inpatient international normalized ratio levels owing to antiphospholi...

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Main Authors: Kalyan R. Chitturi, DO, Miguel A. Castro, MD, Eric Salazar, MD, Michael Deavers, MD, Su Min Chang, MD, John J. Mahmarian, MD, Karla M. Kurrelmeyer, MD
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:JACC: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084920301492
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spelling doaj-4acbac78a4b64db68bc61cd8c73492862021-06-07T06:55:41ZengElsevierJACC: Case Reports2666-08492020-04-0124539543Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic EndocarditisKalyan R. Chitturi, DO0Miguel A. Castro, MD1Eric Salazar, MD2Michael Deavers, MD3Su Min Chang, MD4John J. Mahmarian, MD5Karla M. Kurrelmeyer, MD6Houston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasAddress for correspondence: Dr. Miguel A. Castro, Houston Methodist DeBakey Heart & Vascular Institute, 6550 Fannin Street, Suite 1901, Houston, Texas 77030.; Houston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasHouston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasHouston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasHouston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasHouston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasHouston Methodist DeBakey Heart & Vascular Institute, Houston Methodist, Houston, TexasA 54-year-old woman with a mechanical mitral valve replacement presented with recurrent admissions for pneumonia and pulmonary edema. Multimodality imaging revealed mobile masses on the prosthesis and discrepant point of care and inpatient international normalized ratio levels owing to antiphospholipid antibody cross-reactivity on the outpatient assay. The prosthetic valve thromboses resolved with therapeutic anticoagulation. (Level of Difficulty: Beginner.)http://www.sciencedirect.com/science/article/pii/S2666084920301492antiphospholipid syndromeantithrombotic therapiesmitral valve diseasenonbacterial thrombotic endocarditisprosthetic valve thrombosis
collection DOAJ
language English
format Article
sources DOAJ
author Kalyan R. Chitturi, DO
Miguel A. Castro, MD
Eric Salazar, MD
Michael Deavers, MD
Su Min Chang, MD
John J. Mahmarian, MD
Karla M. Kurrelmeyer, MD
spellingShingle Kalyan R. Chitturi, DO
Miguel A. Castro, MD
Eric Salazar, MD
Michael Deavers, MD
Su Min Chang, MD
John J. Mahmarian, MD
Karla M. Kurrelmeyer, MD
Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
JACC: Case Reports
antiphospholipid syndrome
antithrombotic therapies
mitral valve disease
nonbacterial thrombotic endocarditis
prosthetic valve thrombosis
author_facet Kalyan R. Chitturi, DO
Miguel A. Castro, MD
Eric Salazar, MD
Michael Deavers, MD
Su Min Chang, MD
John J. Mahmarian, MD
Karla M. Kurrelmeyer, MD
author_sort Kalyan R. Chitturi, DO
title Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
title_short Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
title_full Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
title_fullStr Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
title_full_unstemmed Mechanical Mitral Valve Thrombosis in a Patient With Prior Nonbacterial Thrombotic Endocarditis
title_sort mechanical mitral valve thrombosis in a patient with prior nonbacterial thrombotic endocarditis
publisher Elsevier
series JACC: Case Reports
issn 2666-0849
publishDate 2020-04-01
description A 54-year-old woman with a mechanical mitral valve replacement presented with recurrent admissions for pneumonia and pulmonary edema. Multimodality imaging revealed mobile masses on the prosthesis and discrepant point of care and inpatient international normalized ratio levels owing to antiphospholipid antibody cross-reactivity on the outpatient assay. The prosthetic valve thromboses resolved with therapeutic anticoagulation. (Level of Difficulty: Beginner.)
topic antiphospholipid syndrome
antithrombotic therapies
mitral valve disease
nonbacterial thrombotic endocarditis
prosthetic valve thrombosis
url http://www.sciencedirect.com/science/article/pii/S2666084920301492
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