Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression.

Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression.

A well-established approach for detecting genes involved in tumorigenesis due to copy number alterations (CNAs) is to assess the recurrence of the alteration across multiple samples. Expression data can be used to filter this list of candidates by assessing whether the gene expression significantly...

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Bibliographic Details
Main Authors:	David Tamborero, Nuria Lopez-Bigas, Abel Gonzalez-Perez
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23408991/pdf/?tool=EBI

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