Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone

Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone

To find out effective anticancer compounds we synthesized (1–30) derivatives of 4-isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12, 23, 26 and 28 showed better activities ranging (0.39–1.1 µg/ml) than the standard (1.53 ± 0.01 µg/ml). In line with this, compou...

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Bibliographic Details
Main Authors:	Muhammad Taha, Sadia Sultan, Muhammad Herizal, M. Qaiser Fatmi, Manikandan Selvaraj, Kalavathy Ramasamy, Sobia Ahsan Halim, Siong Meng Lim, Fazal Rahim, Kamran Ashraf, Adeeb Shehzad
Format:	Article
Language:	English
Published:	Elsevier 2019-12-01
Series:	Journal of Saudi Chemical Society
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319610319300808

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