Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis
Frontotemporal Dementia (FTD) is a common cause of Young Onset Dementia and has diverse clinical manifestations involving behavior, executive function, language and motor function, including parkinsonism. Up to 50% of FTD patients report a positive family history, supporting a strong genetic basis,...
Main Authors: | Jacqueline Dominguez, Jeryl Tan Yu, Yi Jayne Tan, Arlene Ng, Ma Fe De Guzman, Boots Natividad, Ma Luisa Daroy, Jemellee Cano, Justine Yu, Michelle M. Lian, Li Zeng, Weng Khong Lim, Jia Nee Foo, Adeline S. L. Ng |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-05-01
|
Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2021.645913/full |
Similar Items
-
ALS-Related Mutant SOD1 Aggregates Interfere with Mitophagy by Sequestering the Autophagy Receptor Optineurin
by: Yeong Jin Tak, et al.
Published: (2020-10-01) -
Editorial: The Role of Optineurin in Immunity and Immune-Mediated Diseases
by: Andrew M. Smith, et al.
Published: (2019-12-01) -
Listeriolysin O Regulates the Expression of Optineurin, an Autophagy Adaptor That Inhibits the Growth of Listeria monocytogenes
by: Madhu Puri, et al.
Published: (2017-09-01) -
Implication de l’appareil de Golgi et de l’ubiquitination dans l’activation de TBK1 après détection des ARNs viraux
by: Pourcelot, Marie
Published: (2016) -
Optineurin Functions for Optimal Immunity
by: Karolina Slowicka, et al.
Published: (2018-04-01)