Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function

Cochlear hair cells convert sound-induced vibration into electrical signals. FAM65B mutations cause hearing loss by an unknown mechanism. Using biochemistry and stochastic optical reconstruction microscopy (STORM), we show here that Fam65b oligomers form a circumferential ring near the basal taper o...

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Bibliographic Details
Main Authors: Bo Zhao, Zizhen Wu, Ulrich Müller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14222