Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function
Cochlear hair cells convert sound-induced vibration into electrical signals. FAM65B mutations cause hearing loss by an unknown mechanism. Using biochemistry and stochastic optical reconstruction microscopy (STORM), we show here that Fam65b oligomers form a circumferential ring near the basal taper o...
Main Authors: | Bo Zhao, Zizhen Wu, Ulrich Müller |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/14222 |
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