Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation

Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation

Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hosp...

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Main Authors: Giovanni Varotti, Ferdinando Dodi, Anna Marchese, Alessia Terulla, Massimo Bertocchi, Iris Fontana
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2016/7920951
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spelling doaj-4b1dec53a6764fb6b506c89c434ef4432020-11-24T23:40:03ZengHindawi LimitedCase Reports in Transplantation2090-69432090-69512016-01-01201610.1155/2016/79209517920951Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas TransplantationGiovanni Varotti0Ferdinando Dodi1Anna Marchese2Alessia Terulla3Massimo Bertocchi4Iris Fontana5Kidney Transplant Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyDepartment of Infectious Disease, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyDepartment of Microbiology, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyKidney Transplant Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyKidney Transplant Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyKidney Transplant Unit, IRCCS San Martino University Hospital, IST National Institute for Cancer Research, Genoa, ItalyCarbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hospitalization and organ procurement, information concerning the donor CR-KP positivity arrived only 72 hours after transplant. Based on this experience, we believe that knowledge of the donor’s CR-KP status should be mandatory before procurement and, if positive, pancreas donation should be contraindicated.http://dx.doi.org/10.1155/2016/7920951
collection DOAJ
language English
format Article
sources DOAJ
author Giovanni Varotti
Ferdinando Dodi
Anna Marchese
Alessia Terulla
Massimo Bertocchi
Iris Fontana
spellingShingle Giovanni Varotti
Ferdinando Dodi
Anna Marchese
Alessia Terulla
Massimo Bertocchi
Iris Fontana
Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
Case Reports in Transplantation
author_facet Giovanni Varotti
Ferdinando Dodi
Anna Marchese
Alessia Terulla
Massimo Bertocchi
Iris Fontana
author_sort Giovanni Varotti
title Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_short Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_full Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_fullStr Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_full_unstemmed Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_sort fatal donor-derived carbapenem-resistant klebsiella pneumoniae infection in a combined kidney-pancreas transplantation
publisher Hindawi Limited
series Case Reports in Transplantation
issn 2090-6943
2090-6951
publishDate 2016-01-01
description Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hospitalization and organ procurement, information concerning the donor CR-KP positivity arrived only 72 hours after transplant. Based on this experience, we believe that knowledge of the donor’s CR-KP status should be mandatory before procurement and, if positive, pancreas donation should be contraindicated.
url http://dx.doi.org/10.1155/2016/7920951
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