Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy

Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts, play a critical role in the compartmentalization of signaling pathways. Physical segregation of proteins in lipid rafts may modulate the accessibility of proteins to regulatory or effector molecules. Thus, lipid...

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Bibliographic Details
Main Authors: Faustino Mollinedo, Consuelo Gajate
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520436132

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