Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability.

<h4>Background and purpose</h4>Vascular calcification, recapitulating bone formation, has a profound impact on plaque stability. The aim of the present study was to determine the influence of bone-like vascular calcification (named osteoid metaplasia = OM) and of osteoprotegerin on plaqu...

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Main Authors: Jean-Michel Davaine, Thibaut Quillard, Régis Brion, Olivier Lapérine, Béatrice Guyomarch, Thierry Merlini, Mathias Chatelais, Florian Guilbaud, Meadhbh Áine Brennan, Céline Charrier, Dominique Heymann, Yann Gouëffic, Marie-Françoise Heymann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107642