Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest

Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest

Abstract Background Infant cardiac surgery with cardiopulmonary bypass results in decreased circulating alkaline phosphatase that is associated with poor postoperative outcomes. Bovine intestinal alkaline phosphatase infusion represents a novel therapy for post-cardiac surgery organ injury. However,...

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Bibliographic Details
Main Authors: Ludmila Khailova, Justin Robison, James Jaggers, Richard Ing, Scott Lawson, Amy Treece, Danielle Soranno, Suzanne Osorio Lujan, Jesse A. Davidson
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Inflammation
Subjects:
Cardiac surgery
Organ injury
Inflammation
Endotoxin
Acute kidney injury
Acute lung injury
Online Access:http://link.springer.com/article/10.1186/s12950-020-00256-2

Internet

http://link.springer.com/article/10.1186/s12950-020-00256-2

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