Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model

Abstract Background Topical administration of PR022, 0.05% hypochlorous acid (HOCl) in gel has been demonstrated to be beneficial in a chronic murine atopic dermatitis model. In a follow up study we tested a higher concentration (0.1%) of PR022 HOCl gel in comparison to the Janus kinase inhibitor to...

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Bibliographic Details
Main Authors: Tomoki Fukuyama, Sarah Ehling, Jenny Wilzopolski, Wolfgang Bäumer
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
IgE
Online Access:http://link.springer.com/article/10.1186/s40360-018-0232-3