Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction

• Main Authors: Syed Ahamed Raheel, Omar Bashar Kujan, Bassel Tarakji, Dilshad Umar, Salah Ibrahim
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016-01-01
• Series: Journal of Advanced Pharmaceutical Technology & Research
• Subjects: Acrofacial dysostosis, gingival hyperplasia, Nager syndrome
• Online Access: http://www.japtr.org/article.asp?issn=2231-4040;year=2016;volume=7;issue=2;spage=64;epage=68;aulast=Raheel

Drug reactions are a group of reactionary lesions generally show their manifestations in the oral cavity. The drug reactions may vary from local rashes to well-developed swellings in the oral cavity especially involving the gingiva. Most of the drug reactions are asymptomatic and commonly triggered from the active metabolite of a drug used for a long time. Nager syndrome is a group of acrofacial dysostosis that usually results in craniofacial and limb malformations. The craniofacial defects are very similar to the mandibulofacial dysostosis. A very early intervention is needed for the habilitation of the patient especially when it is concerned with speech and language development. This paper reports a case of a 32-year-old female with craniofacial, limb, and skeletal abnormalities along with a drug-induced gingival hyperplasia.