Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil
Introduction: Chlamydia trachomatis (CT) is the most prevalent sexually transmitted bacterial infection, affecting mainly young, sexually active women. Untreated infection may lead to reproductive complications due to tubal damage. Infections during pregnancy may cause preterm labor, low birth weigh...
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2016-10-01
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doaj-4b63ec357f7f45dfad4bfced5731f4a32020-11-25T01:01:47ZengHospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS)Clinical and Biomedical Research0101-55752357-97302016-10-0136330815Chlamydia trachomatis infection in infertile and pregnant women in southern BrazilDeborah Beltrami Gomez0Ivan Sereno Montenegro1Guilherme Rezende Baade2Paula Barros Terraciano3Raquel de Almeida Schneider4Débora Helena Zanini Gotardi5Victória Furquim dos Santos Cardoso6Eduardo Pandolfi Passos7Universidade Federal do Rio Grande do SulUFRGSUFRGSUFRGSHCPAHCPAHCPAUFRGSIntroduction: Chlamydia trachomatis (CT) is the most prevalent sexually transmitted bacterial infection, affecting mainly young, sexually active women. Untreated infection may lead to reproductive complications due to tubal damage. Infections during pregnancy may cause preterm labor, low birth weight, perinatal death, and neonatal conjunctivitis and pneumonia. There are few data on CT infection in Brazil. The aim of this study was to determine CT prevalence in infertile and pregnant women. Methods: A cross-sectional study included 77 infertile and 60 asymptomatic pregnant women. First-void urine was tested for CT using PCR (Polymerase Chain Reaction). Blood samples were collected for CT IgG antibodies testing using indirect immunofluorescence. A questionnaire about medical, gynecological, and sexual history was completed by all participants. Results: We found statistically similar prevalence of PCR and IgG antibodies between the groups. There was a 61% prevalence of CT IgG antibodies in infertile women and 56.7% in pregnant women. PCR was positive in only one (1.3%) infertile woman and in none pregnant women. Conclusion: There is a high prevalence of CT IgG antibody in Brazilian pregnant and infertile women, but we found a low prevalence of positive PCR in the urine samples. CT antibodies were associated with sexual behavior and smoking. Keywords: Chlamydia trachomatis, Chlamydia infections, prevalence, nucleic acid amplification techniques; infertility, female; fluorescent antibody techniquehttp://seer.ufrgs.br/index.php/hcpa/article/view/65188Chlamydia trachomatisChlamydia infectionsprevalenceNucleic Acid Amplification TechniquesInfertility, femaleFluorescent Antibody Technique |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Deborah Beltrami Gomez Ivan Sereno Montenegro Guilherme Rezende Baade Paula Barros Terraciano Raquel de Almeida Schneider Débora Helena Zanini Gotardi Victória Furquim dos Santos Cardoso Eduardo Pandolfi Passos |
spellingShingle |
Deborah Beltrami Gomez Ivan Sereno Montenegro Guilherme Rezende Baade Paula Barros Terraciano Raquel de Almeida Schneider Débora Helena Zanini Gotardi Victória Furquim dos Santos Cardoso Eduardo Pandolfi Passos Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil Clinical and Biomedical Research Chlamydia trachomatis Chlamydia infections prevalence Nucleic Acid Amplification Techniques Infertility, female Fluorescent Antibody Technique |
author_facet |
Deborah Beltrami Gomez Ivan Sereno Montenegro Guilherme Rezende Baade Paula Barros Terraciano Raquel de Almeida Schneider Débora Helena Zanini Gotardi Victória Furquim dos Santos Cardoso Eduardo Pandolfi Passos |
author_sort |
Deborah Beltrami Gomez |
title |
Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil |
title_short |
Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil |
title_full |
Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil |
title_fullStr |
Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil |
title_full_unstemmed |
Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil |
title_sort |
chlamydia trachomatis infection in infertile and pregnant women in southern brazil |
publisher |
Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) |
series |
Clinical and Biomedical Research |
issn |
0101-5575 2357-9730 |
publishDate |
2016-10-01 |
description |
Introduction: Chlamydia trachomatis (CT) is the most prevalent sexually transmitted bacterial infection, affecting mainly young, sexually active women. Untreated infection may lead to reproductive complications due to tubal damage. Infections during pregnancy may cause preterm labor, low birth weight, perinatal death, and neonatal conjunctivitis and pneumonia. There are few data on CT infection in Brazil. The aim of this study was to determine CT prevalence in infertile and pregnant women.
Methods: A cross-sectional study included 77 infertile and 60 asymptomatic pregnant women. First-void urine was tested for CT using PCR (Polymerase Chain Reaction). Blood samples were collected for CT IgG antibodies testing using indirect immunofluorescence. A questionnaire about medical, gynecological, and sexual history was completed by all participants.
Results: We found statistically similar prevalence of PCR and IgG antibodies between the groups. There was a 61% prevalence of CT IgG antibodies in infertile women and 56.7% in pregnant women. PCR was positive in only one (1.3%) infertile woman and in none pregnant women.
Conclusion: There is a high prevalence of CT IgG antibody in Brazilian pregnant and infertile women, but we found a low prevalence of positive PCR in the urine samples. CT antibodies were associated with sexual behavior and smoking.
Keywords: Chlamydia trachomatis, Chlamydia infections, prevalence, nucleic acid amplification techniques; infertility, female; fluorescent antibody technique |
topic |
Chlamydia trachomatis Chlamydia infections prevalence Nucleic Acid Amplification Techniques Infertility, female Fluorescent Antibody Technique |
url |
http://seer.ufrgs.br/index.php/hcpa/article/view/65188 |
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