Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases

Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases

Oxaliplatin, a platinum-based chemotherapeutic agent, is responsible for induced peripheral sensory neuropathy. Only a few cases of ophthalmologic toxicity have been reported. We report here two cases of sudden transient vision loss after oxaliplatin administration, in one case intraperitoneally. Th...

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Main Authors: Loic Ah-Thiane, Jean-Luc Raoul, Sandrine Hiret, Hélène Senellart, Frédéric Dumont, Judith Raimbourg
Format: Article
Language:English
Published: Karger Publishers 2021-03-01
Series:Case Reports in Oncology
Subjects:
oxaliplatin
sight loss
acute ocular toxicity
optic neuritis
Online Access:https://www.karger.com/Article/FullText/514656
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spelling doaj-4b9377f097744fe4a1af090036a17c632021-04-15T14:58:48ZengKarger PublishersCase Reports in Oncology1662-65752021-03-0114148348610.1159/000514656514656Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two CasesLoic Ah-Thiane0Jean-Luc Raoul1https://orcid.org/0000-0001-6305-8953Sandrine Hiret2Hélène Senellart3Frédéric Dumont4Judith Raimbourg5Department of Medical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceDepartment of Medical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceDepartment of Medical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceDepartment of Medical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceDepartment of Surgical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceDepartment of Medical Oncology, Institut de Cancérologie de l’Ouest, Saint-Herblain, FranceOxaliplatin, a platinum-based chemotherapeutic agent, is responsible for induced peripheral sensory neuropathy. Only a few cases of ophthalmologic toxicity have been reported. We report here two cases of sudden transient vision loss after oxaliplatin administration, in one case intraperitoneally. These symptoms likely reflect optic neuritis that could be included in the spectrum of oxaliplatin-induced neuropathy.https://www.karger.com/Article/FullText/514656oxaliplatinsight lossacute ocular toxicityoptic neuritis
collection DOAJ
language English
format Article
sources DOAJ
author Loic Ah-Thiane
Jean-Luc Raoul
Sandrine Hiret
Hélène Senellart
Frédéric Dumont
Judith Raimbourg
spellingShingle Loic Ah-Thiane
Jean-Luc Raoul
Sandrine Hiret
Hélène Senellart
Frédéric Dumont
Judith Raimbourg
Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
Case Reports in Oncology
oxaliplatin
sight loss
acute ocular toxicity
optic neuritis
author_facet Loic Ah-Thiane
Jean-Luc Raoul
Sandrine Hiret
Hélène Senellart
Frédéric Dumont
Judith Raimbourg
author_sort Loic Ah-Thiane
title Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
title_short Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
title_full Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
title_fullStr Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
title_full_unstemmed Transient Vision Loss – A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases
title_sort transient vision loss – a rare oxaliplatin-induced ophthalmologic side effect: a report of two cases
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2021-03-01
description Oxaliplatin, a platinum-based chemotherapeutic agent, is responsible for induced peripheral sensory neuropathy. Only a few cases of ophthalmologic toxicity have been reported. We report here two cases of sudden transient vision loss after oxaliplatin administration, in one case intraperitoneally. These symptoms likely reflect optic neuritis that could be included in the spectrum of oxaliplatin-induced neuropathy.
topic oxaliplatin
sight loss
acute ocular toxicity
optic neuritis
url https://www.karger.com/Article/FullText/514656
work_keys_str_mv AT loicahthiane transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
AT jeanlucraoul transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
AT sandrinehiret transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
AT helenesenellart transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
AT fredericdumont transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
AT judithraimbourg transientvisionlossarareoxaliplatininducedophthalmologicsideeffectareportoftwocases
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