Predicting the Solubility of Pharmaceutical Cocrystals in Solvent/Anti-Solvent Mixtures

In this work, the solubilities of pharmaceutical cocrystals in solvent/anti-solvent systems were predicted using PC-SAFT in order to increase the efficiency of cocrystal formation processes. Modeling results and experimental data were compared for the cocrystal system nicotinamide/succinic acid (2:1...

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Bibliographic Details
Main Authors: Linda Lange, Stefan Heisel, Gabriele Sadowski
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/5/593