Optogenetic translocation of protons out of penumbral neurons is protective in a rodent model of focal cerebral ischemia
Background: Intracellular acidosis in the ischemic penumbra can contribute to further cell death, effectively enlarging the infarct core. Restoring the acid-base balance may enhance tissue survivability after cerebral ischemia. Objective: This study investigated whether translocating protons out of...
Main Authors: | Bin Bo, Yao Li, Wanlu Li, Yongting Wang, Shanbao Tong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | Brain Stimulation |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1935861X20300619 |
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