Molecular Biosensing Mechanisms in the Spleen for the Removal of Aged and Damaged Red Cells from the Blood Circulation

Molecular Biosensing Mechanisms in the Spleen for the Removal of Aged and Damaged Red Cells from the Blood Circulation

Heinz bodies are intraerythrocytic inclusions of hemichrome formed as a result of hemoglobin (Hb) oxidation. They typically develop in aged red cells. Based on the hypothesis that hemichrome formation is an innate characteristic of physiologically normal Hb molecules, we present an overview of our p...

Full description

Bibliographic Details
Main Authors: Eriko Ueno, Ikumi Ohgushi, Yoko Abe, Yuki Shigemasa, Yuko Hayashi, Yoshiaki Sugawara, Fumio Shimamoto
Format: Article
Language:English
Published: MDPI AG 2010-07-01
Series:Sensors
Subjects:
biosensing
Heinz body formation
hemichrome formation
normal human erythrocytes
spleen
Online Access:http://www.mdpi.com/1424-8220/10/8/7099/

Internet

http://www.mdpi.com/1424-8220/10/8/7099/

Similar Items