Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma
Objective: Neck management in cT1-2N0 tongue squamous cell carcinoma (SCC) remains controversial. Our goal was to compare the survival difference between PET-CT–guided neck dissection and elective neck dissection (END) for the treatment of cT1-2 tongue SCC.Methods: Patients with surgically treated c...
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doaj-4ba72ccfc8ff48b9a4b54cbd6f6f568c2020-11-25T03:25:52ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2020-06-011010.3389/fonc.2020.00720519298Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell CarcinomaFengjie Zhu0Shuhan Sun1Kai Ba2Department of Oral Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Oral Medicine, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Oral Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaObjective: Neck management in cT1-2N0 tongue squamous cell carcinoma (SCC) remains controversial. Our goal was to compare the survival difference between PET-CT–guided neck dissection and elective neck dissection (END) for the treatment of cT1-2 tongue SCC.Methods: Patients with surgically treated cT1-2N0 tongue SCC were retrospectively enrolled. These patients were divided into two groups. Group A: The decision of whether to perform neck dissection was mainly based on the results of preoperative PET-CT examinations. Group B: Patients received END treatment without preoperative PET-CT examinations. The study endpoints were regional control (RC) and disease-specific survival (DSS). The Kaplan–Meier method was used to calculate the survival rates.Results: Group A consisted of 66 patients, and 16 patients underwent neck dissection owing to positive PET-CT results. Group B consisted of 169 patients. The 5-year RC rates in group A and group B were 86 and 87%, respectively, and the difference was not significant (p = 0.731). The 5-year DSS rates in group A and group B were 93 and 90%, respectively, and the difference was not significant (p = 0.583).Conclusions: Neck dissection can be safely avoided when the PET-CT scan reveals no neck lymph node involvement.https://www.frontiersin.org/article/10.3389/fonc.2020.00720/fullPET-CTelective neck dissectionsurvival analysisearly stage tongue cancertongue squamous cell carcinoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fengjie Zhu Shuhan Sun Kai Ba |
spellingShingle |
Fengjie Zhu Shuhan Sun Kai Ba Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma Frontiers in Oncology PET-CT elective neck dissection survival analysis early stage tongue cancer tongue squamous cell carcinoma |
author_facet |
Fengjie Zhu Shuhan Sun Kai Ba |
author_sort |
Fengjie Zhu |
title |
Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma |
title_short |
Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma |
title_full |
Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma |
title_fullStr |
Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma |
title_full_unstemmed |
Comparison Between PET-CT–Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma |
title_sort |
comparison between pet-ct–guided neck dissection and elective neck dissection in ct1-2n0 tongue squamous cell carcinoma |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Oncology |
issn |
2234-943X |
publishDate |
2020-06-01 |
description |
Objective: Neck management in cT1-2N0 tongue squamous cell carcinoma (SCC) remains controversial. Our goal was to compare the survival difference between PET-CT–guided neck dissection and elective neck dissection (END) for the treatment of cT1-2 tongue SCC.Methods: Patients with surgically treated cT1-2N0 tongue SCC were retrospectively enrolled. These patients were divided into two groups. Group A: The decision of whether to perform neck dissection was mainly based on the results of preoperative PET-CT examinations. Group B: Patients received END treatment without preoperative PET-CT examinations. The study endpoints were regional control (RC) and disease-specific survival (DSS). The Kaplan–Meier method was used to calculate the survival rates.Results: Group A consisted of 66 patients, and 16 patients underwent neck dissection owing to positive PET-CT results. Group B consisted of 169 patients. The 5-year RC rates in group A and group B were 86 and 87%, respectively, and the difference was not significant (p = 0.731). The 5-year DSS rates in group A and group B were 93 and 90%, respectively, and the difference was not significant (p = 0.583).Conclusions: Neck dissection can be safely avoided when the PET-CT scan reveals no neck lymph node involvement. |
topic |
PET-CT elective neck dissection survival analysis early stage tongue cancer tongue squamous cell carcinoma |
url |
https://www.frontiersin.org/article/10.3389/fonc.2020.00720/full |
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