Optimization of Cyanine Dye Stability and Analysis of FRET Interaction on DNA Microarrays

Optimization of Cyanine Dye Stability and Analysis of FRET Interaction on DNA Microarrays

The application of DNA microarrays for high throughput analysis of genetic regulation is often limited by the fluorophores used as markers. The implementation of multi-scan techniques is limited by the fluorophores’ susceptibility to photobleaching when exposed to the scanner laser light. This paper...

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Bibliographic Details
Main Authors: Marcel von der Haar, Christopher Heuer, Martin Pähler, Kathrin von der Haar, Patrick Lindner, Thomas Scheper, Frank Stahl
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Biology
Subjects:
microarray
DNA
scanning
photobleaching
fluorophore
cyanine dye
FRET
ROXS
bioinformatics
bioanalytics
Online Access:http://www.mdpi.com/2079-7737/5/4/47

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