Vapor detection and discrimination with a panel of odorant receptors

Vapor detection and discrimination with a panel of odorant receptors

Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sensor able to discriminate structurally similar compou...

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Main Authors: Hitoshi Kida, Yosuke Fukutani, Joel D. Mainland, Claire A. de March, Aashutosh Vihani, Yun Rose Li, Qiuyi Chi, Akemi Toyama, Linda Liu, Masaharu Kameda, Masafumi Yohda, Hiroaki Matsunami
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06806-w
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spelling doaj-4bb70edca5cc4c01907d20a917e267272021-05-11T09:55:37ZengNature Publishing GroupNature Communications2041-17232018-11-019111010.1038/s41467-018-06806-wVapor detection and discrimination with a panel of odorant receptorsHitoshi Kida0Yosuke Fukutani1Joel D. Mainland2Claire A. de March3Aashutosh Vihani4Yun Rose Li5Qiuyi Chi6Akemi Toyama7Linda Liu8Masaharu Kameda9Masafumi Yohda10Hiroaki Matsunami11Department of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterDepartment of Mechanical Systems Engineering, Tokyo University of Agriculture and TechnologyDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and TechnologyDepartment of Molecular Genetics and Microbiology, Duke University Medical CenterBiomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sensor able to discriminate structurally similar compounds.https://doi.org/10.1038/s41467-018-06806-w
collection DOAJ
language English
format Article
sources DOAJ
author Hitoshi Kida
Yosuke Fukutani
Joel D. Mainland
Claire A. de March
Aashutosh Vihani
Yun Rose Li
Qiuyi Chi
Akemi Toyama
Linda Liu
Masaharu Kameda
Masafumi Yohda
Hiroaki Matsunami
spellingShingle Hitoshi Kida
Yosuke Fukutani
Joel D. Mainland
Claire A. de March
Aashutosh Vihani
Yun Rose Li
Qiuyi Chi
Akemi Toyama
Linda Liu
Masaharu Kameda
Masafumi Yohda
Hiroaki Matsunami
Vapor detection and discrimination with a panel of odorant receptors
Nature Communications
author_facet Hitoshi Kida
Yosuke Fukutani
Joel D. Mainland
Claire A. de March
Aashutosh Vihani
Yun Rose Li
Qiuyi Chi
Akemi Toyama
Linda Liu
Masaharu Kameda
Masafumi Yohda
Hiroaki Matsunami
author_sort Hitoshi Kida
title Vapor detection and discrimination with a panel of odorant receptors
title_short Vapor detection and discrimination with a panel of odorant receptors
title_full Vapor detection and discrimination with a panel of odorant receptors
title_fullStr Vapor detection and discrimination with a panel of odorant receptors
title_full_unstemmed Vapor detection and discrimination with a panel of odorant receptors
title_sort vapor detection and discrimination with a panel of odorant receptors
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-11-01
description Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sensor able to discriminate structurally similar compounds.
url https://doi.org/10.1038/s41467-018-06806-w
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