Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b

The KRAS gene encodes two isoforms, KRas4a and KRas4b. Differences in the signaling functions of the two KRas proteins are poorly understood. Here we report the comparative and nucleotide-dependent interactomes of KRas4a and KRas4b. Many previously unknown interacting proteins were identified, with...

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Bibliographic Details
Main Authors: Xiaoyu Zhang, Ji Cao, Seth P. Miller, Hui Jing, Hening Lin
Format: Article
Language:English
Published: American Chemical Society 2017-12-01
Series:ACS Central Science
Online Access:http://dx.doi.org/10.1021/acscentsci.7b00440

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