Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden
The risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2019-05-01
|
Series: | Journal of Community Hospital Internal Medicine Perspectives |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/20009666.2019.1601059 |
id |
doaj-4bc3766f09c94c4288f6abd2915239f2 |
---|---|
record_format |
Article |
spelling |
doaj-4bc3766f09c94c4288f6abd2915239f22020-11-25T00:11:39ZengTaylor & Francis GroupJournal of Community Hospital Internal Medicine Perspectives2000-96662019-05-019326426610.1080/20009666.2019.16010591601059Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V LeidenSoluny Jean0Interfaith Medical CenterThe risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients using POC, including patients with a medical condition associated with an increased risk of thrombosis. Therefore, no specific consideration is warranted when using a POC in healthy young females, regardless of an inherited thrombophilia. We present a case of a young woman who has Factor V Leiden (FVL), presenting with an isolated pulmonary embolism (PE) while using a progesterone containing intrauterine device (IUD). The risk of VTE in FVL carriers seems to outweigh the benefit of contraception even when using progestin-only contraception. Therefore, non-hormonal contraception, such as copper IUD, seems to be the only safe alternative for contraception in this population. Further studies are needed to elucidate this observation. Abbreviation: PE: pulmonary embolism; FVL: factor V Leiden; VTE: venous thromboembolism; POC: progestin only contraception; CBC: complete blood count; CMP: complete metabolic panel; ABG: arterial Blood gas; CTPA: CT pulmonary angiographyhttp://dx.doi.org/10.1080/20009666.2019.1601059Factor V Leidenpulmonary embolismprogestin-only contraceptioncopper IUDprogestin IUDvenous thromboembolism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Soluny Jean |
spellingShingle |
Soluny Jean Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden Journal of Community Hospital Internal Medicine Perspectives Factor V Leiden pulmonary embolism progestin-only contraception copper IUD progestin IUD venous thromboembolism |
author_facet |
Soluny Jean |
author_sort |
Soluny Jean |
title |
Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
title_short |
Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
title_full |
Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
title_fullStr |
Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
title_full_unstemmed |
Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
title_sort |
isolated pulmonary embolism in a patient with progestin intrauterine device and factor v leiden |
publisher |
Taylor & Francis Group |
series |
Journal of Community Hospital Internal Medicine Perspectives |
issn |
2000-9666 |
publishDate |
2019-05-01 |
description |
The risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients using POC, including patients with a medical condition associated with an increased risk of thrombosis. Therefore, no specific consideration is warranted when using a POC in healthy young females, regardless of an inherited thrombophilia. We present a case of a young woman who has Factor V Leiden (FVL), presenting with an isolated pulmonary embolism (PE) while using a progesterone containing intrauterine device (IUD). The risk of VTE in FVL carriers seems to outweigh the benefit of contraception even when using progestin-only contraception. Therefore, non-hormonal contraception, such as copper IUD, seems to be the only safe alternative for contraception in this population. Further studies are needed to elucidate this observation. Abbreviation: PE: pulmonary embolism; FVL: factor V Leiden; VTE: venous thromboembolism; POC: progestin only contraception; CBC: complete blood count; CMP: complete metabolic panel; ABG: arterial Blood gas; CTPA: CT pulmonary angiography |
topic |
Factor V Leiden pulmonary embolism progestin-only contraception copper IUD progestin IUD venous thromboembolism |
url |
http://dx.doi.org/10.1080/20009666.2019.1601059 |
work_keys_str_mv |
AT solunyjean isolatedpulmonaryembolisminapatientwithprogestinintrauterinedeviceandfactorvleiden |
_version_ |
1725402885718540288 |