Advances and challenges in adeno-associated viral inner-ear gene therapy for sensorineural hearing loss

Advances and challenges in adeno-associated viral inner-ear gene therapy for sensorineural hearing loss

There is growing attention and effort focused on treating the root cause of sensorineural hearing loss rather than managing associated secondary characteristic features. With recent substantial advances in understanding sensorineural hearing-loss mechanisms, gene delivery has emerged as a promising...

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Bibliographic Details
Main Authors: Kamakshi Bankoti, Charles Generotti, Tiffany Hwa, Lili Wang, Bert W. O’Malley, Jr., Daqing Li
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
AAV
inner ear
sensorineural hearing loss
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000450

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