Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia
Objective To analyze neuropsychiatric symptoms in patients with vascular dementia (VaD). Methods Neuropsychiatric Inventory (NPI), Mini ⁃ Mental State Examination (MMSE) and Hachinski Ischemia Score (HIS) were used to assess the neuropsychiatric symptoms in 81 cases with VaD, 35 cases with post⁃stro...
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Tianjin Huanhu Hospital
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doaj-4bee0e65ab904bf6b5c6a853a757576a2020-11-24T21:08:47ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312010-06-01103342346461Clinical analysis of neuropsychiatric symptoms in patients with vascular dementiaHong⁃fang CHENHui⁃jun SHAOYi⁃ping CHENJian⁃qin LUOYa⁃ming FUObjective To analyze neuropsychiatric symptoms in patients with vascular dementia (VaD). Methods Neuropsychiatric Inventory (NPI), Mini ⁃ Mental State Examination (MMSE) and Hachinski Ischemia Score (HIS) were used to assess the neuropsychiatric symptoms in 81 cases with VaD, 35 cases with post⁃stroke non⁃dementia (PS⁃ND), 58 cases with Alzheimer's disease (AD) and 61 cases with normal elders as control group. Results Presentation of delusion, hallucination, agitation, depression and (or) dysthymia, apathy, irritability and (or) lability, aberrant action behavior, and NPI total scores in VaD group were significantly more than those in control group (P < 0.05 or P < 0.01). Delusion was more often seen in AD group than that in VaD group, and the difference was significant (P < 0.01). Hallucination, anxiety, apathy, irritability and (or) lability, and aberrant action behavior were significantly different among VaD with different severity (P < 0.05 or P < 0.01). These symptoms were all more obvious along with the patients' condition. Conclusion Various neuropsychiatric symptoms in VaD are similar to those in AD. The predominant neuropsychiatric symptoms are emotional and affective disturbance in patients with moderate and severe VaD. DOI:10.3969/j.issn.1672-6731.2010.03.013http://www.cjcnn.org/index.php/cjcnn/article/view/462Dementia, vascularAlzheimer diseaseNeuropsychological tests |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hong⁃fang CHEN Hui⁃jun SHAO Yi⁃ping CHEN Jian⁃qin LUO Ya⁃ming FU |
spellingShingle |
Hong⁃fang CHEN Hui⁃jun SHAO Yi⁃ping CHEN Jian⁃qin LUO Ya⁃ming FU Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia Chinese Journal of Contemporary Neurology and Neurosurgery Dementia, vascular Alzheimer disease Neuropsychological tests |
author_facet |
Hong⁃fang CHEN Hui⁃jun SHAO Yi⁃ping CHEN Jian⁃qin LUO Ya⁃ming FU |
author_sort |
Hong⁃fang CHEN |
title |
Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
title_short |
Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
title_full |
Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
title_fullStr |
Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
title_full_unstemmed |
Clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
title_sort |
clinical analysis of neuropsychiatric symptoms in patients with vascular dementia |
publisher |
Tianjin Huanhu Hospital |
series |
Chinese Journal of Contemporary Neurology and Neurosurgery |
issn |
1672-6731 |
publishDate |
2010-06-01 |
description |
Objective To analyze neuropsychiatric symptoms in patients with vascular dementia (VaD). Methods Neuropsychiatric Inventory (NPI), Mini ⁃ Mental State Examination (MMSE) and Hachinski Ischemia Score (HIS) were used to assess the neuropsychiatric symptoms in 81 cases with VaD, 35 cases with post⁃stroke non⁃dementia (PS⁃ND), 58 cases with Alzheimer's disease (AD) and 61 cases with normal elders as control group. Results Presentation of delusion, hallucination, agitation, depression and (or) dysthymia, apathy, irritability and (or) lability, aberrant action behavior, and NPI total scores in VaD group were significantly more than those in control group (P < 0.05 or P < 0.01). Delusion was more often seen in AD group than that in VaD group, and the difference was significant (P < 0.01). Hallucination, anxiety, apathy, irritability and (or) lability, and aberrant action behavior were significantly different among VaD with different severity (P < 0.05 or P < 0.01). These symptoms were all more obvious along with the patients' condition. Conclusion Various neuropsychiatric symptoms in VaD are similar to those in AD. The predominant neuropsychiatric symptoms are emotional and affective disturbance in patients with moderate and severe VaD.
DOI:10.3969/j.issn.1672-6731.2010.03.013 |
topic |
Dementia, vascular Alzheimer disease Neuropsychological tests |
url |
http://www.cjcnn.org/index.php/cjcnn/article/view/462 |
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