Chronic Exposure to Particulate Nickel Induces Neoplastic Transformation in Human Lung Epithelial Cells

Chronic Exposure to Particulate Nickel Induces Neoplastic Transformation in Human Lung Epithelial Cells

Nickel is a well-known human lung carcinogen with the particulate form being the most potent; however, the carcinogenic mechanism remains largely unknown. Few studies have investigated the genotoxicity and carcinogenicity of nickel in its target cell, human bronchial epithelial cells. Thus, the goal...

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Bibliographic Details
Main Authors: Amie L. Holmes, Therry The, Kelsey Thompson, Michael Mason, Sanjeev Kandpal, Tongzhang Zheng, John Pierce Wise
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Toxics
Subjects:
particulate nickel
nickel subsulfide
chromosome damage
transformation
Online Access:http://www.mdpi.com/2305-6304/1/1/46

Internet

http://www.mdpi.com/2305-6304/1/1/46

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