Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.
Developing thymocytes undergo a rigorous selection process to ensure that the mature T cell population expresses a T cell receptor (TCR) repertoire that can functionally interact with major histocompatibility complexes (MHC). Over 90% of thymocytes fail this selection process and die. A small number...
Main Authors: | Hye-Jung Kim, Eric S Alonzo, Guillaume Dorothee, Jeffrey W Pollard, Derek B Sant'Angelo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2897847?pdf=render |
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