Prophylactic effects or withdrawal reactions? An analysis of time-to-event data from antidepressant relapse prevention trials submitted to the FDA
Background: Relapse prevention trials build the scientific foundation for recommendation of antidepressant continuation and maintenance therapy. However, the validity of the evidence is disputed and may be biased due to withdrawal confounding. Methods: We analysed survival curves from all antidepres...
Main Authors: | Michael P. Hengartner, Martin Plöderl |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-08-01
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Series: | Therapeutic Advances in Psychopharmacology |
Online Access: | https://doi.org/10.1177/20451253211032051 |
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