Decreased PGE₂ content reduces MMP-1 activity and consequently increases collagen density in human varicose vein.
Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear.In this study, we investigated the control of matrix metalloproteinases (MMPs) expression by prostaglandin (PG)E₂ during the vascular wall remodeling of human varic...
Main Authors: | Ingrid Gomez, Chabha Benyahia, Liliane Louedec, Guy Leséche, Marie-Paule Jacob, Dan Longrois, Xavier Norel |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3914898?pdf=render |
Similar Items
-
Reverse Regulatory Pathway (H2S / PGE2 / MMP) in Human Aortic Aneurysm and Saphenous Vein Varicosity.
by: Ingrid Gomez, et al.
Published: (2016-01-01) -
Varicose Vein
by: Putri Septiani, et al.
Published: (2016-05-01) -
The Effect of Varicose Vein Surgery on Varicose Ulcers
by: Abbas Saroukhani, et al.
Published: (2020-05-01) -
Surgery in Varicose Veins
by: Hassanein A. Hussein, et al.
Published: (2014-01-01) -
Two applications of microwave therapy : psoriasis and varicose veins
by: Guy, Adam John
Published: (2004)