PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein that regulates hepatic low-density lipoprotein receptor (LDLR) levels in humans. PCSK9 has also been shown to regulate the levels of additional membrane-bound proteins in vitro, including the very low-density lipoprotein rec...

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Bibliographic Details
Main Authors: Mali Liu, Guoxin Wu, Jennifer Baysarowich, Michael Kavana, George H. Addona, Kathleen K. Bierilo, John S. Mudgett, Guillaume Pavlovic, Ayesha Sitlani, John J. Renger, Brian K. Hubbard, Timothy S. Fisher, Celina V. Zerbinatti
Format: Article
Language:English
Published: Elsevier 2010-09-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
low-density lipoprotein
proprotein convertase subtilisin/kexin type 9
β-site amyloid precursor protein-cleaving enzyme 1
amyloid-β
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520422916

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http://www.sciencedirect.com/science/article/pii/S0022227520422916

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