Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides

Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides

Background: Evidence suggests that earlier diagnosis and initiation of treatment immediately after birth is critical for improved neurodevelopmental outcomes following neonatal encephalopathy (NE). Current diagnostic tests are, however, mainly restricted to clinical diagnosis with no molecular tests...

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Bibliographic Details
Main Authors: Edward Beamer, Mary Isabel O’Dea, Aisling A. Garvey, Jonathon Smith, Aida Menéndez-Méndez, Lynne Kelly, Andreea Pavel, Sean Quinlan, Mariana Alves, Eva M. Jimenez-Mateos, Faming Tian, Eugene Dempsey, Nicholas Dale, Deirdre M. Murray, Geraldine B. Boylan, Eleanor J. Molloy, Tobias Engel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neonatal encephalopathy
biomarker
purines
mouse models
clinical testing
seizures
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.732199/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.732199/full

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