The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo.
Human lymphatic filariasis is a major tropical disease transmitted through mosquito vectors which take up microfilarial larvae from the blood of infected subjects. Microfilariae are produced by long-lived adult parasites, which also release a suite of excretory-secretory products that have recently...
Main Authors: | James P Hewitson, Dominik Rückerl, Yvonne Harcus, Janice Murray, Lauren M Webb, Simon A Babayan, Judith E Allen, Agnes Kurniawan, Rick M Maizels |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586152/pdf/?tool=EBI |
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