Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

<p>Abstract</p> <p>Although highly penetrant alleles of <it>BRCA1 </it>and <it>BRCA2 </it>have been shown to predispose to breast cancer, the majority of breast cancer cases are assumed to result from the presence of low-moderate penetrant alleles and enviro...

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Bibliographic Details
Main Authors:	Savas Sevtap, Schmidt Steffen, Jarjanazi Hamdi, Ozcelik Hilmi
Format:	Article
Language:	English
Published:	BMC 2006-03-01
Series:	Human Genomics
Subjects:	breast cancer predisposition nsSNPs breast tissue expression carcinogenesis-related genes PolyPhen
Online Access:	http://www.humgenomics.com/content/2/5/287

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