Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo

Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo

Mitochondrial complex I inhibition has been implicated in the degeneration of midbrain dopaminergic (DA) neurons in Parkinson's disease. However, the mechanisms and pathways that determine the cellular fate of DA neurons downstream of the mitochondrial dysfunction have not been fully identified...

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Bibliographic Details
Main Authors:	B.H. Meurers, C. Zhu, P.O. Fernagut, F. Richter, Y.C. Hsia, S.M. Fleming, M. Oh, D. Elashoff, C.D. DiCarlo, R.L. Seaman, M.F. Chesselet
Format:	Article
Language:	English
Published:	Elsevier 2009-02-01
Series:	Neurobiology of Disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996108002519

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